The show tells the story of 24-year-old Sazae, who’s married with child and lives with her parents and younger siblings.
Families get together and watch the show each Sunday, so its appeal is probably wider any weekly TV anime.
In the original manga, Sazae was a feminist, didn’t think the man was the head of the household and joined the women’s liberation movement.
If you are learning Japanese, this is the anime to watch.
That way, as you watch, you can learn useful and applicable things about Japan and Japanese culture, unlike some anime which paint a far more abstract view of the country.